Cage compounds; metal-complex
catalysis; directed enantioselective synthesis; medicinal chemistry;
chromenes; methylene quinones, molecular modeling.
synthesis/reductive rearrangement of 2-acyl-2,3-dihydrofuranes as a
base of a novel methodology of polyfunctional 4H-pyranes preparing.
- Chiral Michael
adducts in stereoselective synthesis of non-aromatic heterocyclic
methides cycloaddiction reactions as the key step to flavonoids and
Dearomatization of highly polarized five-membered heterocycles as a
novel methodology in organic synthesis.
Terminal-disubstituted sterically hindered 2-butenes in synthesis of
carbo- and heterocyclic systems.
1,3-Disubstituted 2-oxaadamantanes as a molecular platform for
structure-various polyfunctional heterocage systems.
design of ion channel blockers of (+)-RNA genomic viruses based on
saturated cage heterocycles.
- Development of
an approach to multitarget inhibitors used against the SARS-CoV2
reproduction by directed design of cage ligands for the E ion channel
and the nsp13 helicase.
- Development of
novel approaches to synthesis of non-racemic carbo- and heterocyclic
systems based on intramolecular oxidative addition/carbometallation
Transformations of sterically hindered epihalohydrin analogues.
at The Center of
Collective Use «Research of Physical and Chemical Properties of
Substances and Materials»
20-53-04035\20 RFBR (Shiryaev V.A.).
The contest of
the best projects of basic science researches, that are being
performed in cooperation between the young researchers’ teams from
The Russian Federation and The Republic of Belarus, that is being
held in cooperation between the Federal government budgetary
institution «Russian Foundation for Basic Research» and
«Belarusian Republican Foundation for Fundamental Research».